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Rabbit Anti-mucolipin 2  antibody (bs-18730R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-18730R
英文名稱 Rabbit Anti-mucolipin 2  antibody
中文名稱 粘脂蛋白2抗體
別    名 Mcoln2; 3300002C04Rik ; AI549968 ; FLJ36691 ; MCOLN2 ; mucolipin 2 ; TRP ML2 ; TRPML2.  
研究領域 腫瘤  細胞生物  信號轉導  跨膜蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 66kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human mucolipin 2 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009]

Function:
Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV.

Subcellular Location:
Membrane; Multi-pass membrane protein.

SWISS:
Q8IZK6

Gene ID:
255231

Database links:

Entrez Gene: 255231 Human

SwissProt: Q8IZK6 Human



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