| 產品編號 | bs-18723R |
| 英文名稱 | Rabbit Anti-MCF2L2 antibody |
| 中文名稱 | MCF2變換序列樣蛋白2抗體 |
| 別 名 | ARHGEF22; Dbs related Rho family guanine nucleotide exchange factor; Dbs-related Rho family guanine nucleotide exchange factor; DKFZp686K0690; DRG; FLJ42509; KIAA0861; MCF.2 cell line derived transforming sequence like 2; MCF2 transforming sequence like protein 2; MCF2-transforming sequence-like protein 2; MCF2L2; MF2L2_HUMAN; Probable guanine nucleotide exchange factor MCF2L2; Rho family guanine nucleotide exchange factor. |
| 研究領域 | 腫瘤 細胞生物 神經生物學 信號轉導 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human) |
| 產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 127kDa |
| 細胞定位 | 細胞核 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MCF2L2: 741-840/1114 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
MCF2L2 is a 1,114 amino acid protein that contains one spectrin repeat, one PH domain, one DH domain and one CRAL-TRIO domain. Expressed at high levels in brain and also present in testis and pancreas, MCF2L2 is thought to function as a GEF, catalyzing the activation of target GTPases. Variations in the gene encoding MCF2L2 may be associated with an increased susceptibility to type 2 diabetes. Multiple isoforms of MCF2L2 exist due to alternative splicing events. Function: Probably functions as a guanine nucleotide exchange factor. Tissue Specificity: Significantly expressed in brain and modestly in pancreas, brain and testis. DISEASE: Genetic variation in MCF2L2 may be associated with susceptibility to noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type 2. Similarity: Belongs to the MCF2 family. Contains 1 CRAL-TRIO domain. Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. Contains 1 spectrin repeat. SWISS: Q86YR7 Gene ID: 23101 Database links: Entrez Gene: 23101 Human SwissProt: Q86YR7 Human Unigene: 208267 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
