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Rabbit Anti-MARS2  antibody (bs-18683R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-18683R
英文名稱 Rabbit Anti-MARS2  antibody
中文名稱 甲硫氨酸轉運RNA合成酶2抗體
別    名 mars2; Methionine tRNA ligase 2; Methionine tRNA ligase 2 mitochondrial; Methionine tRNA ligase; Methionine tRNA synthetase 2; Methionine--tRNA ligase; Methionyl tRNA synthetase 2 mitochondrial; Methionyl tRNA synthetase mitochondrial; Methionyl-tRNA synthetase 2; MetRS; mitochondrial; Mitochondrial methionine tRNA ligase; Mitochondrial methionyl tRNA synthetase; Mitochondrial methionyl-tRNA synthetase; MtMetRS; SYMM_HUMAN.  
研究領域 細胞生物  神經生物學  信號轉導  轉運蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 63kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MARS2: 31-130/593 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]

DISEASE:
Spastic ataxia 3, autosomal recessive (SPAX3) [MIM:611390]: A neurologic disorder characterized by cerebellar ataxia, ataxic gait, spasticity, and hyperreflexia. Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

SWISS:
Q96GW9

Gene ID:
92935

Database links:

Entrez Gene: 92935 Human

Omim: 609728 Human

SwissProt: Q96GW9 Human

Unigene: 116602 Human

Unigene: 744330 Human



產品圖片
Sample: Stomach (Rat) Lysate at 40 ug Primary: Anti-MARS2 (bs-18683R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kD Observed band size: 65 kD
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