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Rabbit Anti-LIPA3  antibody (bs-18287R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-18287R
英文名稱 Rabbit Anti-LIPA3  antibody
中文名稱 蛋白酪氨酸磷酸酶受體F多肽α3抗體
別    名 LIPA3_HUMAN; liprin; Liprin-alpha-3; LPNA3; Ppfia3; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3; PTPRF-interacting protein alpha-3.  
研究領域 細胞生物  神經生物學  信號轉導  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 133kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIPA3: 301-400/1194 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The Drosophila segment polarity gene lin encodes a protein, lines, which plays important roles in development of the epidermis and hindgut. This gene encodes a protein containing a lines-like domain. This gene is located on chromosome 15 and clustered with the gene encoding ankyrin repeat and SOCS box-containing protein 7. [provided by RefSeq, Sep 2010]

Function:
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.

Subcellular Location:
Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.

Tissue Specificity:
Expressed only in brain.

Similarity:
Belongs to the liprin family. Liprin-alpha subfamily.
Contains 3 SAM (sterile alpha motif) domains.

SWISS:
O75145

Gene ID:
8541

Database links:

Entrez Gene: 8541 Human

Entrez Gene: 76787 Mouse

Entrez Gene: 140591 Rat

Omim: 603144 Human

SwissProt: O75145 Human

SwissProt: P60469 Mouse

SwissProt: Q91Z79 Rat

Unigene: 413748 Human

Unigene: 277235 Mouse

Unigene: 105437 Rat



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