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Rabbit Anti-MTHFD2  antibody (bs-17877R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-17877R
英文名稱 Rabbit Anti-MTHFD2  antibody
中文名稱 亞甲基四氫葉酸脫氫酶2抗體
別    名 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Descriptions; methenyltetrahydrofolate cyclohydrolase; methylene tetrahydrofolate dehydrogenase (NAD+ dependent); methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent); methylenetetrahydrofolate dehydrogenase 2; MGC82516; MTDC_HUMAN; MTHFD2; mthfd2 methylene tetrahydrofolate dehydrogenase (NAD+ dependent); NAD-dependent methylene tetrahydrofolate dehydrogenase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC.  
研究領域 細胞生物  免疫學  信號轉導  轉錄調節因子  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Horse,Xenopus laevis)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 36kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTHFD2: 201-300/350 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

SWISS:
P13995

Gene ID:
10797

Database links:

Entrez Gene: 10797 Human

Entrez Gene: 441024 Human

Entrez Gene: 17768 Mouse

Entrez Gene: 665563 Mouse

Entrez Gene: 305248 Rat

Entrez Gene: 680308 Rat

Omim: 604887 Human

SwissProt: Q5ZKA5 Chicken

SwissProt: Q0P5C2 Cow

SwissProt: P13995 Human

SwissProt: Q9H903 Human

SwissProt: D3YZG8 Mouse

SwissProt: P18155 Mouse

SwissProt: D3ZUA0 Rat

Unigene: 469030 Human

Unigene: 721011 Human

Unigene: 740700 Human

Unigene: 740707 Human

Unigene: 153030 Mouse

Unigene: 443 Mouse

Unigene: 475021 Mouse

Unigene: 11744 Rat

Unigene: 206715 Rat



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