產(chǎn)品編號(hào) | bs-17814R |
英文名稱 | Rabbit Anti-MRPS17 antibody |
中文名稱 | 線粒體核糖體蛋白S17抗體 |
別 名 | 1810006P02Rik; 28S ribosomal protein S17; 28S ribosomal protein S17 mitochondrial; HSPC011; mitochondrial; Mitochondrial ribosomal protein S17; MRP S17; MRP-S17; mrps17; OTTHUMP00000209315; OTTMUSP00000034583; OTTMUSP00000034585; OTTMUSP00000034586; OTTMUSP00000034588; OTTMUSP00000034590; OTTMUSP00000034591; OTTMUSP00000034592; RPMS17; RT17_HUMAN; S17mt. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 線粒體 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 12kDa |
細(xì)胞定位 | 細(xì)胞核 線粒體 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MRPS17: 21-100/130 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008] Subunit: Component of the mitochondrial ribosome small subunit Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein S17P family. SWISS: Q9Y2R5 Gene ID: 51373 Database links: Entrez Gene: 51373 Human Entrez Gene: 66258 Mouse Omim: 611980 Human SwissProt: Q9Y2R5 Human SwissProt: Q9CQE3 Mouse Unigene: 44298 Human Unigene: 249809 Mouse |