| 產(chǎn)品編號 | bs-16481R |
| 英文名稱 | Rabbit Anti-ZNF768 antibody |
| 中文名稱 | 鋅指蛋白768抗體 |
| 別 名 | FLJ23436; Zinc finger protein 768; ZN768_HUMAN; ZNF768. |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF768: 1-100/540 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 768 (ZNF768) is a 540 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF768 contains ten C2H2-type zinc fingers through which it is thought to be involved in DNA-binding and transcriptional regulation. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 10 C2H2-type zinc fingers. SWISS: Q9H5H4 Gene ID: 79724 Database links: Entrez Gene: 79724 Human Entrez Gene: 233890 Mouse SwissProt: Q9H5H4 Human SwissProt: Q8R0T2 Mouse Unigene: 85658 Human Unigene: 23031 Mouse |
