產(chǎn)品編號 | bs-10690R |
英文名稱 | Rabbit Anti-phospho-Ephrin B1 (Tyr317) antibody |
中文名稱 | 磷酸化Ephrin B1抗體 |
別 名 | phospho-Ephrin B1 (phospho Y317); Ephrin B (phospho Y317); p-Ephrin B (phospho Y317); phospho-Ephrin B1 (Tyr317); phospho-Ephrin B2(Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN. |
產(chǎn)品類型 | 磷酸化抗體 |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 生長因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Cow,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 34kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human Ephrin B1 around the phosphorylation site of Tyr317: PH(p-Y)EK |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. Subunit: Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein. Tissue Specificity: Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments. Post-translational modifications: Membrane; single pass type I membrane protein. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. SWISS: P52799 Gene ID: 1947 Database links: Entrez Gene: 1947 Human Entrez Gene: 13641 Mouse Omim: 300035 Human SwissProt: P98172 Human SwissProt: P52795 Mouse Unigene: 144700 Human Unigene: 3374 Mouse Unigene: 44398 Rat |