| 產品編號 | bs-14367R |
| 英文名稱 | Rabbit Anti-DNAH8 antibody |
| 中文名稱 | 軸絲動力蛋白8抗體 |
| 別 名 | ATPase; DYH8_HUMAN; Axonemal beta dynein heavy chain 8; Ciliary dynein heavy chain 8; dynein axonemal heavy chain 8; dynein axonemal heavy polypeptide 8; dynein heavy chain 8 axonemal; hdhc9; RP1-202I21.7. |
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Specific References (1) | bs-14367R has been referenced in 1 publications.
[IF=11.025] Chaofeng Tu. et al. Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. Am J Hum Genet. 2021 Jul;: IF ; Human.
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| 研究領域 | 細胞生物 信號轉導 細胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Dog,Horse) |
| 產品應用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 514kDa |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAH8: 601-700/4490 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012] Function: Dyneins are microtubule-associated motor protein complexes which are composed of several heavy, light, and intermediate chains. Dynein heavy chains (DHCs) are responsible for force production and ATPase activity and contain a highly conserved catalytic domain with 4 P-loop consensus motifs involved in nucleotide binding. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. Axonemal dyneins, found in flagella and cilia, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH8 is an outer arm axonemal DHC. Subunit: Consists of at least two heavy chains and a number of intermediate and light chains. Subcellular Location: Cytoplasm, cytoskeleton, cilium axoneme (By similarity). Similarity: Belongs to the dynein heavy chain family. SWISS: Q96JB1 Gene ID: 1769 Database links: Entrez Gene: 1769 Human Omim: 603337 Human SwissProt: Q96JB1 Human Unigene: 520106 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
