產(chǎn)品編號 | bs-14117R |
英文名稱 | Rabbit Anti-EOLA1/CXorf40A antibody |
中文名稱 | 內(nèi)皮細(xì)胞高表達(dá)脂多糖相關(guān)因子1抗體 |
別 名 | CX04A_HUMAN; CXorf40A; Endothelial-overexpressed lipopolysaccharide-associated factor 1; EOLA1; Protein CXorf40A. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 內(nèi)皮細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 18kDa |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EOLA1/CXorf40A: 21-120/158 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
EOLA1 is a 158 amino acid protein that may have a role in cell protection during an inflammation reaction. EOLA1 is expressed at high levels in skeletal muscle, liver, kidney, heart and placenta, with lower expression found in colon, small intestine and spleen. EOLA1 interacts with Metallothionein 2A, a member of the Metallothionein family. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Due to their essential role in the protection of cells against the toxicity of cadmium, mercury, and copper, metallothioneins are implicated primarily in metal ion detoxification. Metallothionein, as an acute phase or stress-response protein and free radical scavenger, is related to inflammation and cellular protection from reactive forms of oxygen, ionizing radiation, pharmacological agents and mutagens. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Function: May have an important role of cell protection in inflammation reaction. Tissue Specificity: Expressed primarily in heart, skeletal muscle, kidney, liver and placenta. Relatively high level of expression in spleen, colon and small intestine. Almost no expression in brain, thymus, lung and peripheral blood leukocytes. SWISS: Q8TE69 Gene ID: 91966 Database links: Entrez Gene: 91966 Human SwissProt: Q8TE69 Human Unigene: 534641 Human |