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Rabbit Anti-FAT4  antibody (bs-13721R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-13721R
英文名稱 Rabbit Anti-FAT4  antibody
中文名稱 鈣粘蛋白14抗體
別    名 CDHF14; FAT4_HUMAN; Cadherin family member 14; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J; FATJ; hFat4; Nbla00548; Protocadherin Fat 4.  
研究領域 腫瘤  細胞生物  信號轉導  細胞粘附分子  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 538kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDHF14: 4351-4450/4981 <Extracellular>
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014]

Function:
May function in the regulation of planar cell polarity. Cadherins are cell-cell interaction molecules.

Subcellular Location:
Membrane. In the kidney, localizes to primary cilia.

Tissue Specificity:
Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.

Similarity:
Contains 34 cadherin domains.
Contains 6 EGF-like domains.
Contains 2 laminin G-like domains.

SWISS:
Q6V0I7

Gene ID:
79633

Database links:

Entrez Gene: 79633 Human

SwissProt: Q6V0I7 Human

Unigene: 563205 Human



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