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Rabbit Anti-HoxC13  antibody (bs-13599R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-13599R
英文名稱 Rabbit Anti-HoxC13  antibody
中文名稱 同源盒蛋白HOX13抗體
別    名 ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-C13; Hox-3G; HOX3; HOX3G; HOXC13; HXC13; NUP98.  
Specific References  (3)     |     bs-13599R has been referenced in 3 publications.
[IF=2.752] Yanyu He. et al. Altered Hypoxia-Induced and Heat Shock Protein Immunostaining in Secondary Hair Follicles Associated with Changes in Altitude and Temperature in Tibetan Cashmere Goats. Animals-Basel. 2021 Oct;11(10):2798  IF,IHC ;  goat.  
[IF=1.343] He et al. Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed. (2015) Anat.Rec.(Hoboken). 298:1796-803  IHC-P ;  Goat.  
[IF=1.34] He, Yanyu, et al. "Determination of secondary follicle characteristics, density, activity and Hoxc13 expression pattern of Hexi cashmere goats breed." The Anatomical Record (2015).  IHC-P ;  Goat.  
研究領(lǐng)域 細胞生物  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HoxC13: 231-330/330 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla.

Function:
HOXC13 is a member of a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms and provide cells with specific positional identities on the anterior-posterior axis. HOXC13 is a sequence-specific transcription factor that may play a role in the development of hair, nail, and filiform papilla.

Subcellular Location:
Nuclear

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
P31276

Gene ID:
3229

Database links:

Entrez Gene: 3229 Human

Entrez Gene: 538716 Cow

Entrez Gene: 15422 Mouse

Omim: 142976 Human

SwissProt: P31276 Human

SwissProt: P50207 Mouse



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