產(chǎn)品編號 | bs-13599R |
英文名稱 | Rabbit Anti-HoxC13 antibody |
中文名稱 | 同源盒蛋白HOX13抗體 |
別 名 | ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-C13; Hox-3G; HOX3; HOX3G; HOXC13; HXC13; NUP98. |
Specific References (3) | bs-13599R has been referenced in 3 publications.
[IF=2.752] Yanyu He. et al. Altered Hypoxia-Induced and Heat Shock Protein Immunostaining in Secondary Hair Follicles Associated with Changes in Altitude and Temperature in Tibetan Cashmere Goats. Animals-Basel. 2021 Oct;11(10):2798 IF,IHC ; goat.
[IF=1.343] He et al. Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed. (2015) Anat.Rec.(Hoboken). 298:1796-803 IHC-P ; Goat.
[IF=1.34] He, Yanyu, et al. "Determination of secondary follicle characteristics, density, activity and Hoxc13 expression pattern of Hexi cashmere goats breed." The Anatomical Record (2015). IHC-P ; Goat.
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研究領(lǐng)域 | 細胞生物 干細胞 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 35kDa |
細胞定位 | 細胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HoxC13: 231-330/330 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla. Function: HOXC13 is a member of a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms and provide cells with specific positional identities on the anterior-posterior axis. HOXC13 is a sequence-specific transcription factor that may play a role in the development of hair, nail, and filiform papilla. Subcellular Location: Nuclear Similarity: Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: P31276 Gene ID: 3229 Database links: Entrez Gene: 3229 Human Entrez Gene: 15422 Mouse Omim: 142976 Human SwissProt: P31276 Human SwissProt: P50207 Mouse |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |