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Rabbit Anti-GGT7 light chain  antibody (bs-10459R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-10459R
英文名稱 Rabbit Anti-GGT7 light chain  antibody
中文名稱 γ-谷氨酰轉肽酶7輕鏈抗體
別    名 Gamma-glutamyltransferase 7 light chain; D20S101; dJ18C9.2; Gamma glutamyltransferase 4; Gamma glutamyltransferase 7; Gamma glutamyltransferase like 3; Gamma glutamyltransferase like 5; Gamma glutamyltranspeptidase 7; Gamma glutamyltranspeptidase like 3; GGT 7; GGT4; GGTL3; GGTL5; GGT7_HUMAN.  
研究領域 腫瘤  細胞生物  信號轉導  干細胞  新陳代謝  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GGT7 light chain: 581-662/662 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].

Function:
Cleaves glutathione conjugates

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Isoform 3 interacts with FAM57A.

Subcellular Location:
Membrane; Single pass type II membrane protein.

Tissue Specificity:
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.

Similarity:
Belongs to the gamma-glutamyltransferase family.

SWISS:
Q9UJ14

Gene ID:
2686

Database links:

 



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