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Rabbit Anti-PCSK4  antibody (bs-15501R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-15501R
英文名稱 Rabbit Anti-PCSK4  antibody
中文名稱 原蛋白轉化酶4抗體
別    名 PC4; PCSK4; PCSK4_HUMAN; Proprotein convertase 4; Proprotein convertase PC4; Proprotein convertase subtilisin/kexin type 4.   
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Pig,Cow)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 70kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCSK4: 221-320/755 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 PCSK4 is a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Function:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Placenta.

Similarity:
Belongs to the peptidase S8 family. Furin subfamily.
Contains 1 FU (furin-like) repeat.

SWISS:
Q6UW60

Gene ID:
54760

Database links:

Entrez Gene: 54760 Human

Omim: 600487 Human

SwissProt: Q6UW60 Human

Unigene: 46884 Human



產品圖片
Sample: SY5Y(Human) Cell Lysate at 30 ug Testis (Mouse) Lysate at 40 ug Primary: Anti- PCSK4 (bs-15501R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kD Observed band size: 70 kD
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