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Rabbit Anti-GMFG  antibody (bs-13457R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-13457R
英文名稱 Rabbit Anti-GMFG  antibody
中文名稱 膠漿成熟因子γ/GMF-γ抗體
別    名 Glia maturation factor gamma; Glia maturation factor, gamma; GMF GAMMA; GMF-gamma; Gmfg; GMFG_HUMAN; MGC126867.  
研究領域 細胞生物  轉運蛋白  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GMFG: 51-142/142 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.

Tissue Specificity:
Expressed predominantly in lung, heart and placenta.

Similarity:
Belongs to the actin-binding proteins ADF family.
GMF subfamily.
Contains 1 ADF-H domain.

SWISS:
O60234

Gene ID:
9535

Database links:

Entrez Gene: 9535 Human

Entrez Gene: 63986 Mouse

Entrez Gene: 514407 Cow

Omim: 604104 Human

SwissProt: Q56JZ9 Cow

SwissProt: O60234 Human

SwissProt: Q9ERL7 Mouse

Unigene: 5210 Human

Unigene: 194536 Mouse



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