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Rabbit Anti-CSNK1A1L  antibody (bs-12943R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-12943R
英文名稱 Rabbit Anti-CSNK1A1L  antibody
中文名稱 酪蛋白激酶1/casein kinase Iα抗體
別    名 Casein kinase 1, alpha 1 like; casein kinase 1, alpha 1-like; Casein kinase I alpha S like; Casein kinase I isoform alpha like; CK1; CKI alpha like; MGC33182; OTTHUMP00000018267; RP11 532O21.2; KC1AL_HUMAN.  
研究領(lǐng)域 細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSNK1A1L: 201-300/337 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase I Alpha, I Gamma, I Delta and I Epsilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.

Function:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1A1L can phosphorylate a large number of proteins and participates in Wnt signaling.

Subcellular Location:
Cytoplasmic.

Similarity:
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Contains 1 protein kinase domain

SWISS:
Q8N752

Gene ID:
122011

Database links:

Entrez Gene: 122011 Human

GenBank: NP_660204.2 Human

SwissProt: Q8N752 Human

Unigene: 512897 Human



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