| 產(chǎn)品編號 | bs-12173R |
| 英文名稱 | Rabbit Anti-KCNF1 antibody |
| 中文名稱 | 電壓門控性鉀通道蛋白亞基kv5.1抗體 |
| 別 名 | IK 8; IK8; KCNF 1; KCNF; Kcnf1; KCNF1_HUMAN; kH 1; kH1; KV5.1; Potassium voltage-gated channel subfamily F member 1; MGC33316; Potassium channel KH1; Potassium channel Kv5.1; Potassium voltage gated channel subfamily F member 1; Potassium voltage-gated channel subfamily F member 1; Voltage gated potassium channel subunit Kv5.1; Voltage-gated potassium channel subunit Kv5.1. |
 |
Specific References (1) | bs-12173R has been referenced in 1 publications.
[IF=4.43] Slaats et al. Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesis. (2015) J.Cell.Sc. 128:4550-9 IF,WB ; Mouse.
|
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 56kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNF1: 161-260/494 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas. Function: Putative voltage-gated potassium channel. Subunit: Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1. Subcellular Location: Membrane. Tissue Specificity: Detected in heart, brain, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily. SWISS: Q9H3M0 Gene ID: 3754 Database links: Entrez Gene: 3754 Human Entrez Gene: 382571 Mouse Omim: 603787 Human SwissProt: Q9H3M0 Human SwissProt: Q7TSH7 Mouse Unigene: 23735 Human Unigene: 40173 Mouse |
| 產(chǎn)品圖片 |
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- KCNF1 (bs-12173R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD
|
