| 產品編號 | bs-12108R |
| 英文名稱 | Rabbit Anti-P2RX5 antibody |
| 中文名稱 | 三磷酸腺苷受體P2X5抗體 |
| 別 名 | ATP receptor; ATP receptor subunit; Ionotropic ATP receptor P2X5; LRH 1; LRH1; Lymphoid restricted histocompatibility antigen 1; MGC47755; P2rx5; P2RX5_HUMAN; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; Purinergic receptor P2X5. |
| 研究領域 | 神經生物學 細胞凋亡 通道蛋白 細胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 47kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2RX5: 251-350/422 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. Function: Receptor for ATP that acts as a ligand-gated ion channel. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed at high levels in brain and immune system. Similarity: Belongs to the P2X receptor family. SWISS: Q93086 Gene ID: 5026 Database links: Entrez Gene: 5026 Human Entrez Gene: 94045 Mouse Omim: 602836 Human SwissProt: Q93086 Human Unigene: 408615 Human Unigene: 731607 Human Unigene: 156893 Mouse Unigene: 10257 Rat |
| 產品圖片 |
Sample: Heart (Mouse) Lysate at 40 ug
Primary: Anti-P2RX5 (bs-12108R) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
