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Rabbit Anti-DNAH7  antibody (bs-11023R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-11023R
英文名稱 Rabbit Anti-DNAH7  antibody
中文名稱 軸絲動力蛋白7抗體
別    名 axonemal; Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7; DNAH7; DYH7_HUMAN; Dynein axonemal heavy chain 7; Dynein heavy chain 7; Dynein heavy chain-like protein 2; HDHC2; KIAA0944.  
Specific References  (1)     |     bs-11023R has been referenced in 1 publications.
[IF=9.685] Wu, Huan. et al. DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath. CELL DEATH DIS. 2023 Feb;14(2):1-13  IF ;  Mouse,Human.  
研究領域 神經(jīng)生物學  信號轉(zhuǎn)導  細胞粘附分子  細胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 461kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH7: 2301-2400/4024 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Subunit:
The dynein complex consists of at least two heavy chains and a number of intermediate and light chains (By similarity).

Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.

Tissue Specificity:
Detected in brain, testis and trachea. Detected in bronchial cells (at protein level).

Similarity:
Belongs to the dynein heavy chain family.

SWISS:
Q8WXX0

Gene ID:
56171

Database links:

Entrez Gene: 56171 Human

Omim: 610061 Human

SwissProt: Q8WXX0 Human

Unigene: 97403 Human



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