| 產(chǎn)品編號 | bs-9616R |
| 英文名稱 | Rabbit Anti-C14orf130 antibody |
| 中文名稱 | 14號染色體開放閱讀框130抗體 |
| 別 名 | Chromosome 14 open reading frame 130; N recognin 7; Putative E3 ubiquitin-protein ligase UBR7; Ubiquitin protein ligase E3 component n-recognin 7 (putative); UBR7; UBR 7; UBR-7; UBR7_HUMAN. |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 鋅指蛋白 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 48kDa |
| 細胞定位 | 細胞核 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human UBR7/C14orf130: 331-425/425 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). Similarity: Contains 1 PHD-type zinc finger. Contains 1 UBR-type zinc finger. SWISS: Q8N806 Gene ID: 55148 Database links: Entrez Gene: 55148 Human Entrez Gene: 66622 Mouse Omim: 613816 Human SwissProt: Q8N806 Human SwissProt: Q8BU04 Mouse |
