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Rabbit Anti-WD SOCS box protein 2  antibody (bs-6752R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-6752R
英文名稱 Rabbit Anti-WD SOCS box protein 2  antibody
中文名稱 信號傳導抑制蛋白WD重復蛋白2抗體
別    名 SOCS box containing WD protein SWiP 2; WD 40 repeat containing protein with a SOCS box 2; CS box containing WD protein; SBA2; Swip2; WD repeat and SOCS box containing 2; WD repeat and SOCS box containing protein 2; WD SOCS box protein 2; WSB 2;   
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human WSB2/WD SOCS box protein 2: 51-150/404 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 WSB2 is a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases.

Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Similarity:
Contains 1 SOCS box domain.
Contains 5 WD repeats.

SWISS:
Q9NYS7

Gene ID:
55884

Database links:

Entrez Gene: 55884 Human

Entrez Gene: 59043 Mouse

Entrez Gene: 288692 Rat

SwissProt: Q9NYS7 Human

SwissProt: O54929 Mouse

Unigene: 506985 Human

Unigene: 28489 Mouse

Unigene: 4063 Rat



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