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Rabbit Anti-LRRN5  antibody (bs-6545R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-6545R
英文名稱 Rabbit Anti-LRRN5  antibody
中文名稱 富含亮氨酸重復神經元5抗體
別    名 Fibronectin type III immunoglobulin and leucine rich repeat domain 7; FIGLER7; GAC 1; GAC1; Glioma amplified on chromosome 1; Glioma amplified on chromosome 1 protein; Leucine rich and ankyrin repeats 1; Leucine rich repeat neuronal 2; Leucine rich repeat neuronal 5; Leucine rich repeat neuronal protein 2; Leucine rich repeat neuronal protein 5; LRANK 1; LRANK1; LRRN 2; LRRN 5; LRRN2; LRRN2_HUMAN.  
研究領域 腫瘤  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 77kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRRN5: 601-713/713 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Subcellular Location:
Membrane; Single-pass type I membrane protein

Tissue Specificity:
Overamplified in malignant gliomas.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
O75325

Gene ID:
10446

Database links:

Entrez Gene: 10446 Human

Omim: 605492 Human

SwissProt: O75325 Human

Unigene: 26312 Human



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