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Rabbit Anti-LETMD1  antibody (bs-5937R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-5937R
英文名稱 Rabbit Anti-LETMD1  antibody
中文名稱 宮頸癌原癌基因2抗體
別    名 LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2; LTMD1_HUMAN; HCCR 2; HCCR2.  
研究領域 腫瘤  免疫學  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HCCR2/LETMD1: 21-120/360 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011].

Function:
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.

Subunit:
Interacts with BRI3BP.

Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein.

Tissue Specificity:
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.

Similarity:
Contains 1 LETM1 domain.

SWISS:
Q6P1Q0

Gene ID:
25875

Database links:

Entrez Gene: 25875 Human

Entrez Gene: 68614 Mouse

SwissProt: A3KN46 Cow

SwissProt: Q6P1Q0 Human

SwissProt: Q924L1 Mouse

Unigene: 655272 Human

Unigene: 275272 Mouse



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