| 產品編號 | bs-5846R |
| 英文名稱 | Rabbit Anti-ADAM11 antibody |
| 中文名稱 | 去整合素樣金屬蛋白酶11抗體 |
| 別 名 | A disintegrin and metalloproteinase domain 11; ADA11_HUMAN; MDC; Metalloproteinase like, disintegrin like, and cysteine rich protein. |
| 研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 信號轉導 細胞骨架 細胞外基質 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human,Mouse (predicted: Rat,Sheep,Cow) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 60kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADAM11: 351-450/769 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008]. Function: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Subunit: Can bind to LGI1 and LGI4. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed predominantly in brain. Slightly detected or not at all in other tissues. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Contains 1 disintegrin domain. Contains 1 EGF-like domain. Contains 1 peptidase M12B domain. SWISS: O75078 Gene ID: 4185 Database links: Entrez Gene: 4185 Human Omim: 155120 Human SwissProt: O75078 Human Unigene: 6088 Human 細胞外基質蛋白 |
| 產品圖片 |
Sample: A549 Cell (Human) Lysate at 40 ug
Primary: Anti-ADAM11 (bs-5846R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 60 kD
Sample:
brain (Mouse) Lysate at 40 ug
Primary: Anti-ADAM11 (bs-5846R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 60 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
