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Rabbit Anti-OXCT1  antibody (bs-5089R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-5089R
英文名稱 Rabbit Anti-OXCT1  antibody
中文名稱 含氧酸輔酶A轉移酶1抗體
別    名 mitochondrial; 3 oxoacid CoA transferase 1; 3-oxoacid-CoA transferase 1; OXCT; Oxct1; SCOT; Scot S; Scot-S; SCOT1_HUMAN; Somatic type succinyl CoA:3 oxoacid CoA transferase; Somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; Succinyl CoA:3 ketoacid CoA transferase; Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial; Succinyl CoA:3 oxoacid CoA transferase; Succinyl-CoA:3-ketoacid-coenzyme A transferase 1; EC 2.8.3.5 antibody.  
研究領域 腫瘤  細胞生物  轉錄調節因子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OXCT1: 211-310/520 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.

DISEASE:
Defects in OXCT1 are a cause of SCOT deficiency (SCOTD) [MIM:245050].

Similarity:
Belongs to the 3-oxoacid CoA-transferase family.

SWISS:
P55809

Gene ID:
5019

Database links:

Entrez Gene: 5019 Human

Entrez Gene: 67041 Mouse

Entrez Gene: 690163 Rat

Omim: 601424 Human

SwissProt: P55809 Human

SwissProt: Q9D0K2 Mouse

SwissProt: B2GV06 Rat

Unigene: 278277 Human

Unigene: 13445 Mouse

Unigene: 98472 Rat



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