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Rabbit Anti-Ly75  antibody (bs-2565R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-2565R
英文名稱 Rabbit Anti-Ly75  antibody
中文名稱 淋巴細胞抗原75(CD205)抗體
別    名 LY75_HUMAN; Lymphocyte antigen 75; CD205; CLEC13B; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6;  
研究領(lǐng)域 腫瘤  細胞類型標志物  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,GuineaPig)
產(chǎn)品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 195kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ly75: 601-700/1722 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Function:
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

Post-translational modifications:
N-glycosylated.

Similarity:
Contains 10 C-type lectin domains.
Contains 1 fibronectin type-II domain.
Contains 1 ricin B-type lectin domain.

SWISS:
O60449

Gene ID:
4065

Database links:

Entrez Gene: 4065 Human

Entrez Gene: 17076 Mouse

SwissProt: O60449 Human

SwissProt: Q60767 Mouse



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