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Rabbit Anti-Oxytocin R  antibody (bs-1314R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-1314R
英文名稱 Rabbit Anti-Oxytocin R  antibody
中文名稱 催產素受體(縮宮素受體)抗體
別    名 OXYR_HUMAN; Oxytocin receptor; OXTR; OTR1; OT-R; OTR; OT R; OTR 1; OXT R;   
Specific References  (12)     |     bs-1314R has been referenced in 12 publications.
[IF=8.008] Kaho Nakamura. et al. Probing the Spatiotemporal Dynamics of Oxytocin in the Brain Tissue Using a Simple Peptide Alkyne-Tagging Approach. ANAL CHEM. 2022;94(35):11990–11998  IHC ;  Mouse.  
[IF=4.966] Korie Sondgeroth. et al. The Endometrium Contributes to the Differential Contractile Response to Oxytocin of Uterine Tissue from Virgin and Proven Breeder Non-pregnant Rats. 2021 May 14  IHC ;  Rat.  
[IF=4.473] Tomoki Kumagai. et al. Oxytocin suppresses CXCL10 production in TNF-α-stimulated human dental pulp stem cells. CELL BIOL INT. 2022 Jul;46(9):1530-1535  ICC, WB ;  Human.  
[IF=4.249] Zoratto, F. et al.Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness. (2018) Neuropharmacology.Sep 10;143:250-267.  IHC ;  mouse.  
[IF=4.2] Zhang, Fengwei, et al. "Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus)." Scientific Reports 7.1 (2017): 16627.  WB, IHC-P ;  Others.  
[IF=3.932] Ali II et al. Oxytocin induces intracellular Ca2+ release in cardiac fibroblasts from neonatal rats. Cell Calcium. 2019 Oct 4;84:102099.  ICF ;  Rat.  
[IF=2.445] Yuan Z et al. Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus Dauricus Brandt). Gen Comp Endocrinol. 2020 Apr 1;289:113391.  WB&IHC-P ;  Wild ground squirrel.  
[IF=2.15] Huang, Miaomaio, et al. "The abnormal expression of oxytocin receptors in the uterine junctional zone in women with endometriosis." Reproductive Biology and Endocrinology 15.1 (2017): 1.  IHC-P ;  Human.  
[IF=2.136] Liu Q et al. Seasonal expressions of oxytocin and oxytocin receptor in epididymis of the male muskrat (Ondatra zibethicus).(2018) Theriogenology.124:24-31.  IHC ;  muskrat.  
[IF=2] Zhang, Ying, et al. "Expression of oxytocin receptors in the uterine junctional zone in women with adenomyosis." Acta Obstetricia et Gynecologica Scandinavica (2015).  IHC-P ;  Human.  
[IF=1.974] Raihana Nasrin Ferdousy. et al. Anti-Müllerian hormone stimulates expression of the collagen-specific chaperone 47-kDa heat shock protein in bovine uterine epithelial cells. ANIM SCI J. 2022 Dec;93(1):e13787  IHC ;  Bovine.  
[IF=0] Lim JS et al. Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line. Endocrinol Metab (Seoul). 2019 Sep;34(3):302-313.  IHC-P&ICF ;  Mouse&Rat.  
研究領域 神經生物學  生長因子和激素  細胞膜受體  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat (predicted: Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 43kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse oxytocin receptor: 325-388/388 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 he protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

SWISS:
P97926

Gene ID:
18430

Database links:

Entrez Gene: 281371 Cow

Entrez Gene: 5021 Human

Entrez Gene: 18430 Mouse

Entrez Gene: 397092 Pig

Entrez Gene: 25342 Rat

Omim: 167055 Human

SwissProt: P56449 Cow

SwissProt: P30559 Human

SwissProt: P97926 Mouse

SwissProt: P32306 Pig

SwissProt: P70536 Rat

SwissProt: Q28756 Sheep

Unigene: 2820 Human

Unigene: 333310 Mouse

Unigene: 6841 Rat



OTR在人的子宮平滑肌細胞膜上有縮宮素受體，縮宮素引起子宮收縮的機制可能是通過激活縮宮素受體而實現的。經研究發現，縮宮素受體在外周組織和中樞神經系統內均有分布?？s宮素與不同組織、細胞上的縮宮素受體結合，通過多種信號轉導途徑而發揮作用。
產品圖片
Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (bs-1314R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 53 kD
Sample: Lane 1: Ovary (Mouse) Lysate at 40 ug Lane 2: Cerebrum (Rat) Lysate at 40 ug Lane 3: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (bs-1314R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
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