產品編號 | IHC0288H |
英文名稱 | Human PD-1 Ready-To-Use IHC Kit |
中文名稱 | 人程序性死亡1(CD279)即用型免疫組化試劑盒 |
別 名 | CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; PDCD1; SLEB2; hPD l; PD 1; programmed cell death 1; Protein PD 1 |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產品介紹 |
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE. |
產品圖片 |
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0288H (Human PD-1 IHC Kit).
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1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |